The c-Src (A16) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ASV, c-Src, and Src. This antibody recognizes Human, Mouse, and Rat antigen. The c-Src (A16) Antibody has been validated for the following applications: Immunoprecipitation, and Western Blot.
Description
The Src gene family is represented by at least eight different protein tyrosine kinases belonging to the non-receptor tyrosine kinases (1.2). These protein tyrosine kinases are important regulators of many cellular processes. including cytoskeletal organization. cell-cell contact. DNA synthesis. and cellular proliferation (1-3). Members of this group of proteins include c-Src. c-Yes. Fyn. Lck. Lyn. Hck. Blk and c-Fgr. The proto-oncogene c-Src is the prototype member of this gene family and is expressed in a broad range of tissues and cells (4.5). Elevated c-Src tyrosine kinase activity has been found in many types of human cancers. most notably in breast carcinomas (6.7). The activity of c-Src in these human cancers has been attributed to increases c-Src expression. elevated c-Src specific activity and activating mutations in c-Src (6.7).